Therapeutic Targets Database
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TTD Drug ID: DAP001217

Drug Information
NameBimatoprost    
SynonymsCID5311027; (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide; LS-181817; (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide; D02724; Lumigan (TN); (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide; CHEBI:39562; Bimataprost [USAN:INN:BAN]; AGN-192024; DB06863; CHEBI:51230; NCGC00181745-01; I06-1275; AGN 192024; bimatoprostum; 155206-00-1; Bimatoprost; 5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (5Z)-; 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-1(alpha(Z),2beta(1E,3S*)3alpha,5alpha))-; I06-1277; Bimatoprost (JAN/USAN/INN); Lumigan; AC1NSJUW; UNII-QXS94885MZ; 5-Heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-, (1R-(1alpha(Z),2beta(1E,3S*),3alpha,5alpha))-; Latisse; CHEMBL1200963; DB00905; Bimatoprost [USAN:INN:BAN]; 15M; 267244-98-4; ZINC04474405; 5-Heptenamide,7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ehtyl-,(5Z)    
Trade NameLumigan    
CompanyAllergan Pharmaceuticals    
IndicationOpen-angle glaucoma and ocular hypertensionApproved    [1]
Structure

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Therapeutic ClassAntiglaucomic Agents    
CAS NumberCAS 155206-00-1
FormularC25H37NO4    
PubChem Compound IDCID 5311027.    
PubChem Substance IDSID 704541.    
ChEBI51230;    
SuperDrug ATC IDS01EE03;    
SuperDrug CAS ID155206001;    
TargetProstaglandin F2-alpha receptorAgonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Skin pigmentation after NB-UVB and three analogues of prostaglandin F(2alpha) in guinea pigs: a comparative study. J Eur Acad Dermatol Venereol. 2009 Jul 13. [Epub ahead of print] To Reference



 

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