Therapeutic Targets Database
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TTD Drug ID: DAP001218

Drug Information
NameXimelagatran    
SynonymsH 376/95; Glycine, N-((1R)-1-cyclohexyl-2-((2S)-2-((((4-((hydroxyamino)iminomethyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)-2-oxoethyl)-, ester ester; Ethyl (((1R)-1-cyclohexyl-2-((2S)-2-((4-(hydroxycarbamimidoyl)benzyl)carbamoyl)azetidin-1-yl-2-oxoethyl)amino)acetate; LS-72418; xi-melagatran; Glycine, N-((1R)-1-cyclohexyl-2-((2S)-2-((((4-(hydroxyamino)iminomethyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)-2-oxoethyl)-, ethyl ester; glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester; Ximelagatran; C426686; CID9574101; MolPort-003-850-871; Exanta (TN); Exanta; H 37695; Exarta; Ximelagatran [USAN:INN]; Ximelagatran (JAN/USAN/INN); UNII-49HFB70472; H 376 95; DB04898; H 376-95; H-376/95; Glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-, ethyl ester; Glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester; D01981; 192939-46-1    
Trade NameExanta; Exarta    
CompanyAstraZeneca    
IndicationAnticoagulantApproved    [1]
Structure

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Therapeutic ClassAnticoagulants    
CAS NumberCAS 192939-46-1
FormularC24H35N5O5    
PubChem Compound IDCID 9574101.    
PubChem Substance IDSID 728710.    
SuperDrug ATC IDB01AE05;    
SuperDrug CAS ID192939461;    
TargetProthrombinInhibitor[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes. Toxicol In Vitro. 2009 Jul 16. [Epub ahead of print] To Reference



 

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