Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DAP001245

Drug Information
NameFloxuridine/5-fluorouracil    
Trade NameFUDR    
CompanyRoche Pharmaceuticals    
IndicationColorectal cancerApproved    [1]
Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 50-91-9
FormularC9H11FN2O5    
SuperDrug ATC IDL01BC02;    
SuperDrug CAS ID000051218;    
TargetThymidylate synthaseInhibitor[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Antisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cells. Br J Pharmacol. 1999 Aug;127(8):1777-86. To Reference



 

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