Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP001259

Drug Information
Trade NameMacugen    
CompanyEyetech pharmaceuticals and Pfizer    
IndicationAge-related macular degenerationApproved    [1]
Therapeutic ClassAntiangiogenic Agents    
CAS NumberCAS 222716-86-1
TargetVascular endothelial growth factor Isoform VEGF165Aptamer[2][3]
Ref 1Future pharmacological treatment options for nonexudative and exudative age-related macular degeneration. Expert Opin Emerg Drugs. 2005 Feb;10(1):119-35. To Reference
Ref 2Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006 Feb;5(2):123-32. To Reference
Ref 3Pegaptanib in the treatment of wet, age-related macular degeneration. Int J Nanomedicine. 2006;1(3):263-8. To Reference


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