Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP001340

Drug Information
Name(S)-(+)-Dimethindene maleate    
IndicationPruritusApproved    [1]
Therapeutic ClassAnti-Inflammatory Agents    
CAS NumberCAS 121367-05-3
TargetHistamine H1 receptorAntagonist[2][1][3][4]
Ref 1Prescription and safety of dimethindene maleate micropellet capsules in Hungary. Orv Hetil. 2004 Feb 15;145(7):327-9. To Reference
Ref 2Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors. J Recept Signal Transduct Res. 2009;29(2):84-93. To Reference
Ref 3Effects of dimethindene maleate nasal spray on the quality of life in seasonal allergic rhinitis. Rhinology. 2003 Sep;41(3):159-66. To Reference
Ref 4Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. To Reference


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