Therapeutic Targets Database
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TTD Drug ID: DAP001344

Drug Information
NameAldosterone    
SynonymsAldocortin; Aldosteronum [INN-Latin]; SR-01000838883-2; 11beta,21-Dihydroxypregn-4-ene-3,18,20-trione; 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al; CHEMBL273453; LS-118602; Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)-; (11BETA)-11,21-DIHYDROXY-3,20-DIOXOPREGN-4-EN-18-AL; Aldosterona; 152-04-5; EINECS 200-139-9; Aldosterone, (11 beta,17 alpha)-Isomer; d-Aldosterone; 11beta,21-dihydroxy-3,20-dioxo-pregn-4-ene-18-al; NCGC00164236-01; MLS001333163; 18-Formyl-11beta,21-dihydroxy-4-pregnene-3,20-dione; Reichstein X; NSC 73856; CHEBI:27584; 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al; UNII-4964P6T9RB; Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11-beta)-; Electrocortin; AC1L1L95; 10328-70-8; NSC73856; A9477_SIGMA; (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde; DB04630; Aldocortene; Aldocorten; LMST02030026; BRN 3224996; ZINC03833824; Aldosteronum; 52-39-1; ALDOSTERONE; 18-Oxocorticosterone; 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 18,11-halbacetal; (+)-Aldosterone; BIDD:ER0511; 11beta,21-Dihydroxy-3,20-diketopregn-4-ene-18-al; Aldosterone [INN:BAN:DCF]; SR-01000838883; 18-Aldocorticosterone; Elektrocortin; MLS001333164; CID5839; Aldosterone, (+-)-Isomer; 11beta,21-Dihydroxy-3,20-diketo-4-pregnen-18-al; 4-08-00-03491 (Beilstein Handbook Reference); 11.beta.,21-Dihydroxypregn-4-ene-3,18,20-trione; C01780; SMR000857170; D000450; Aldosterona [INN-Spanish]    
IndicationHypertensionApproved    [1]
Structure

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Therapeutic ClassAntihypertensive Agents    
CAS NumberCAS 52-39-1
FormularC21H28O5    
PubChem Compound IDCID 5839.    
PubChem Substance IDSID 4910.    
ChEBI27584;    
SuperDrug ATC IDH02AA01;    
SuperDrug CAS ID000052391;    
TargetNa-K-2Cl cotransporterBlocker[2][3]
Ref 1Treatment of hypertension with olmesartan medoxomil, alone and in combination with a diuretic: an update. J Hum Hypertens. 2007 Sep;21(9):699-708. Epub 2007 Jun 7. To Reference
Ref 2Nongenomic effect of aldosterone on ion transport pathways of red blood cells. Cell Physiol Biochem. 2008;22(1-4):269-78. Epub 2008 Jul 25. To Reference
Ref 3Aldosterone regulates the Na-K-2Cl cotransporter in vascular smooth muscle. Hypertension. 2003 May;41(5):1131-5. Epub 2003 Mar 31. To Reference



 

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