Therapeutic Targets Database
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TTD Drug ID: DAP001362

Drug Information
NameConnexyn    
SynonymsN-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride; D00606; N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride; SMR000058453; CID71401; BS-100-141; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1); HMS1569C19; Intuniv; EU-0100519; LON 798; N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide hydrochloride; UNII-PML56A160O; GUANFACINE HCL; AC1Q3P39; MLS000069745; N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride; Tenex; n-carbamimidoyl-2-(2,6-dichlorphenyl)acetamidhydrochlorid; guanfacine hydrochloride; Connexyn; C9H9Cl2N3O.HCl; CHEMBL1200494; G 1043; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride; 29110-47-2 (Parent); 29110-48-3; Prestwick_740; Estulic; EINECS 249-443-3; MLS002222252; LS-28474; SPD-503; Guanfacine hydrochloride [USAN:JAN]; Guanfacine hydrochloride (JAN/USP); N-(aminoiminomethyl)-2,6-dichloro-benzeneacetamide hydrochloride; MolPort-003-666-686; NCGC00180965-01; N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride; NCGC00093914-01; BS 100-141; MLS001077329; AR-1K6511; Tenex (TN); AC1L2G3E    
IndicationAttention deficit hyperactivity disorderApproved    [1]
Structure

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Therapeutic ClassCentral Nervous System Agents    
CAS NumberCAS 29110-47-2
FormularC9H10Cl3N3O    
PubChem Compound IDCID 71401.    
PubChem Substance IDSID 213638.    
SuperDrug ATC IDC02AC02;    
SuperDrug CAS ID029110472;    
TargetAlpha-2A adrenergic receptorAgonist[2]
Ref 1Shire Announces NDA Submission of Guanfacine Extended Release for the Treatment of ADHD in Children and Adolescents, 2009 To Reference
Ref 2alpha(2A)-adrenergic receptors heterosynaptically regulate glutamatergic transmission in the bed nucleus of the stria terminalis. Neuroscience. 2009 Jun 12. [Epub ahead of print] To Reference



 

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National University of Singapore, Singapore


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