Therapeutic Targets Database
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TTD Drug ID: DAP001365

Drug Information
NameAntazoline hydrochloride    
Synonyms2-IMIDAZOLINE, 2-((N-BENZYLANILINO)METHYL)-, HYDROCHLORIDE; AC-20133; 2-(N-Phenyl-N-benzylaminomethyl)imidazoline hydrochloride; HMS1568D18; MLS001148371; Fenazolina; NCGC00180986-01; D07459; Prestwick_82; Phenazolinum (TN); 2-(N-Benzylanilino)methyl-2-imidazoline, hydrochloride; Antazoline hydrochloride; Phenazoline hydrochloride; Antazoline HCl; C17H19N3.HCl; Phenazolinum; 91-75-8 (Parent); Antazolinium chloratum; 2-Phenylbenzylaminomethylimidazoline hydrochloride; A9899_SIGMA; N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline hydrochloride; MLS002153486; 2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride; MLS000028599; Antistine hydrochloride; MolPort-003-940-371; MLS002222161; LS-79573; AC1L29OE; UNII-FP8Q8F72JH; 2508-72-7; 2-Imidazoline, 2-((N-benzylanilino)methyl)-, monohydrochloride; SBB057007; CID17275; Histazine; SMR000058731; EINECS 219-719-8    
IndicationOcular allergiesApproved    [1]
Structure

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Therapeutic ClassCentral Nervous System Agents    
CAS NumberCAS 2508-72-7
FormularC17H20ClN3    
PubChem Compound IDCID 17275.    
PubChem Substance IDSID 160456.    
TargetHistamine H1 receptorAntagonist[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018746 To Reference
Ref 2Histamine and the convulsive threshold or effectiveness of antiepileptic drugs. Przegl Lek. 2008;65(11):803-6. To Reference
Ref 3Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice. Eur Neuropsychopharmacol. 2004 Aug;14(4):307-18. To Reference
Ref 4A current appreciation of sites for pharmacological intervention in allergic conjunctivitis: effects of new topical ocular drugs. Acta Ophthalmol Scand Suppl. 1999;(228):33-7. To Reference



 

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