Therapeutic Targets Database
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TTD Drug ID: DAP001366

Drug Information
NameDimethindene    
SynonymsAC1Q4X0G; 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-; Dimetindeno [INN-Spanish]; Z 2001; DIMETHINDENE; TL8003650; Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-; 5-22-11-00123 (Beilstein Handbook Reference); Pecofenil; Dimetindene; Forhistal; Dimethyl{2-[3-(2-pyridylethyl)inden-2-yl]ethyl}amine; Ambap5636-83-9; Fengel; 2-(1-(2-(2-Dimethylaminoethyl)inden-3-yl)ethyl)pyridine; 1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)-; Dimetindenum; EINECS 227-083-8; Dimethpyrindene; LS-131452; Dimethylpyrindene; Dimetindeno; N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine; CID21855; Dimetindene (INN); Dimetindene [INN:BAN]; 1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)- (9CI); (+/-)-Dimethindene; N,N-Dimethyl-N-(3-(1-(2-pyridyl)ethyl)-2-indenylethyl)amin; Fenistil; MolPort-003-986-956; CHEMBL22108; 3614-69-5 (maleate); Dimetindenum [INN-Latin]; N,N-Dimethyl-3-(1-(2-pyridyl)ethyl)inden-2-ethylamin; BRN 0489974; DB08801; Triten; AC1L2J8D; D07853; 5636-83-9; Foristal    
Trade NameFenistil    
IndicationRespiratory allergiesApproved    [1]
Structure

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Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 5636-83-9
FormularC20H24N2    
PubChem Compound IDCID 21855.    
PubChem Substance IDSID 164563.    
SuperDrug ATC IDD04AA13;    
SuperDrug CAS ID005636839;    
TargetHistamine H1 receptorAntagonist[2][1][3][4]
Ref 1Prescription and safety of dimethindene maleate micropellet capsules in Hungary. Orv Hetil. 2004 Feb 15;145(7):327-9. To Reference
Ref 2Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors. J Recept Signal Transduct Res. 2009;29(2):84-93. To Reference
Ref 3Effects of dimethindene maleate nasal spray on the quality of life in seasonal allergic rhinitis. Rhinology. 2003 Sep;41(3):159-66. To Reference
Ref 4Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. To Reference



 

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