Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP001378

Drug Information
NameDimethindene maleate    
SynonymsDimetindene hydrogen maleate; Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-, maleate (1:1); Dimethinden maleate; Dimethindene Malenate; 1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)-, (Z)-2-butenedioate (1:1); Forhistal maleate (TN); Dimetindene maleate; LS-131453; 5636-83-9 (Parent); MLS002704010; C20H24N2.C4H4O4; 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-, (Z)-2-butenedioate (1:1); Pyridine, 2-[1-[2-[2-(dimethylamino)ethyl]inden-3-yl]ethyl]-, maleate (1:1); Forhistal maleate; Forthistal maleate; NSC 107677; Z 820; SMR001570719; AC1NR00Y; Dimetindene maleate (JAN); EINECS 222-789-2; Dimethindene maleate; D01343; Dimethindene maleate (USAN); I14-13956; Dimethindene maleate [USAN]; SU-6518; Dimethpyrindene maleate; UNII-6LL60J9E0O; (Z)-but-2-enedioic acid; N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine; Fenistil; SU 6518; 2-(1-(2-(2-(Dimethylamino)ethyl)inden-3-yl)ethyl)pyridine maleate (1:1); CID5282414; NSC107677; 2-[1-[2-[2-(Dimethylamino)ethyl]inden-3-yl]ethyl]pyridine maleate (1:1); Triten; Fenistil-retard; 2-(1-(2-(2-(Dimethylamino)ethyl)inden-3-yl)ethyl)pyridine maleate; 3614-69-5    
IndicationRespiratory allergiesApproved    [1]

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 3614-69-5
PubChem Compound IDCID 5282414.    
PubChem Substance IDSID 407402.    
TargetHistamine H1 receptorAntagonist[2][1][3][4]
Ref 1Prescription and safety of dimethindene maleate micropellet capsules in Hungary. Orv Hetil. 2004 Feb 15;145(7):327-9. To Reference
Ref 2Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors. J Recept Signal Transduct Res. 2009;29(2):84-93. To Reference
Ref 3Effects of dimethindene maleate nasal spray on the quality of life in seasonal allergic rhinitis. Rhinology. 2003 Sep;41(3):159-66. To Reference
Ref 4Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543