Therapeutic Targets Database
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TTD Drug ID: DAP001403

Drug Information
NameMizolastine    
SynonymsC24H25FN6O; Mizollen; CID65906; AC-634; Schwarz brand of mizolastine; 108612-45-9; Zolistam; Mistalin; UNII-244O1F90NA; CHEBI:252819; MolPort-002-885-879; ST51052747; Mizolastinum; CCRIS 8410; Mizolastine [INN]; SL 85.0324; Novag brand of mizolastine; Mizolastinum [INN-Latin]; Sanofi Synthelabo brand of mizolastine; ZINC13831810; Mizollen (TN); MKC-431; NCGC00181013-01; I06-0373; CHEMBL94454; 2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3H)-pyrimidinone; LS-135935; AC1L247Z; Zolim; SL-85.0324; Mizolastine (JAN/INN); C076170; Zolistan; AKOS005145756; Allphar brand of mizolastine; Mizolastina; Mizolastine; Mistamine; Mizolastina [INN-Spanish]; 4(1H)-Pyrimidinone, 2-((1-(1-((4-fluorophenyl)methyl)-1H-benzimidazol-2-yl)-4-piperidinyl)methylamino)-; Mizolen; Galderma brand of mizolastine; D01117; 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one    
Trade NameMizollen    
IndicationAllergic rhinitisApproved    [1]
Structure

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Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 108612-45-9
FormularC24H25FN6O    
PubChem Compound IDCID 65906.    
PubChem Substance IDSID 207953.    
SuperDrug ATC IDR06AX25;    
SuperDrug CAS ID108612459;    
TargetHistamine H1 receptorAntagonist[2]
Ref 1Population pharmacokinetic analysis and optimization of the experimental design for mizolastine solution in children. J Pharmacokinet Pharmacodyn. 2001 Jun;28(3):299-319. To Reference
Ref 2Histamine H1-receptor antagonists inhibit nuclear factor-kappaB and activator protein-1 activities via H1-receptor-dependent and -independent mechanisms. Clin Exp Allergy. 2008 Jun;38(6):947-56. To Reference



 

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