Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DCL000059

Drug Information
NameAT9283    
CompanyAstex Therape.    
IndicationLeukemia, MyeloidPhase I    
Therapeutic ClassAntineoplastic Agents    
ClinicalTrials.govNCT00522990;    
TargetAurora-AInhibitor[1][2]
Aurora-AMultitarget[1][2]
Aurora-BInhibitor[1][2]
Aurora-BMultitarget[1][2]
Ref 1Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283. Cell Cycle. 2009 Jun 15;8(12):1921-9. Epub 2009 Jun 15. To Reference
Ref 2J Med Chem. 2009 Jan 22;52(2):379-88.Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. To Reference



 

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