Therapeutic Targets Database
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TTD Drug ID: DCL000328

Drug Information
NameXanomeline tartrate    
SynonymsD06331; Memcor; 3-(4-(Hexyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine L-(+)-tartrate (1:1); Xanomeline tartrate [USAN]; AC1Q5R2S; AR-1J3926; LY 246708 tartrate; CID71456; 152854-19-8; AC1L2G75; LS-131634; Pyridine, 3-(4-(hexyloxy0-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl-, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Xanomeline tartrate (USAN); Xanomeline tartrate; Pyridine, 3-(4-(hexyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); (2R,3R)-2,3-dihydroxybutanedioic acid; 3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole    
IndicationAlzheimer's diseasePhase II    

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CAS NumberCAS 152854-19-8
PubChem Compound IDCID 71456.    
PubChem Substance IDSID 213694.    
TargetMuscarinic acetylcholine receptor M1Agonist[1][2]
Ref 1Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6. Epub 2009 Jan 11. To Reference
Ref 2On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor. Mol Pharmacol. 1998 Jun;53(6):1120-30. To Reference


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