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TTD Drug ID: DCL000339

Drug Information
NameNomifensine    
SynonymsCHEMBL273575; KBio1_000789; Nomifensine; Spectrum2_001548; KBio2_001379; KBioSS_001379; L001242; CID4528; NCGC00015727-06; SPBio_002035; Prestwick2_000108; Spectrum5_001004; (+-)-Nomifensin; 8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline; KBio3_001785; nomifensin; 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine 2-butenedioate; 8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate (1:1); 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl; SPBio_001396; LS-85340; D,L-nomifensine; 24526-64-5; Nomifensine Maleate (1:1); Prestwick1_000108; Spectrum3_000963; NINDS_000789; UNII-1LGS5JRP31; IDI1_000789; 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine; Nomifensine [INN:BAN]; Nomifenison; Nomifensina; AB00053664; BRD-A29644307-050-05-5; KBioGR_001438; R/S-nomifensine; Linamiphen; (+)-Nomifensine; LS-85807; BSPBio_000096; Nomiphensine; CHEBI:116225; 8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisochinolin; NCGC00089794-02; 2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine; 32795-47-4 (maleate (1:1)); 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine; (+-)-Nomifensine; Nomifensine maleate(USAN); Nomifensinum; AC1L1IDA; Isoquinoline, 1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-; Prestwick0_000108; BRN 6064059; 118184-50-2; Nomifensina [INN-Spanish]; KBio2_003947; 89664-20-0; CCRIS 9179; 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-; (R)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine; -, (Z)-2-butenedioate (1:1); Spectrum4_001079; BPBio1_000106; 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine; 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl- (9CI); 8-ISOQUINOLINAMINE, 1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-, (R)-; DivK1c_000789; KBio2_006515; LS-85341; Lopac0_000875; DB04821; Prestwick3_000108; BRN 0484561; 8-ISOQUINOLINAMINE, 1,2,3,4-TETRAHYDRO-2-METHYL-4-PHENYL-, (+-)-; 89664-19-7; Spectrum_000899; (+-)-1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine; Nomifensinum [INN-Latin]; 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline; (+)-Nomiphensine; BSPBio_002565    
CompanyUihlein    
IndicationEndogenous depressionWithdrawal    
Structure

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CAS NumberCAS 24526-64-5
FormularC16H18N2    
PubChem Compound IDCID 4528.    
PubChem Substance IDSID 174438.    
SuperDrug ATC IDN06AX04;    
SuperDrug CAS ID024526645;    
TargetD(2) dopamine receptorAntagonist[1][2]
Ref 1Pharmacologically induced, subsecond dopamine transients in the caudate-putamen of the anesthetized rat. Synapse. 2007 Jan;61(1):37-9. To Reference
Ref 2Dopamine D2 receptors: a potential pharmacological target for nomifensine and tranylcypromine but not other antidepressant treatments. Pharmacol Biochem Behav. 1995 Aug;51(4):565-9. To Reference



 

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