Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000341

Drug Information
SynonymsCHEBI:172035; AC1L1TOE; CID60663; DB01388; (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(1-methylethyl)-1,2,3,4-tetrahydronaphthalen-2-yl (methyloxy)acetate; C29H38FN3O3; CHEMBL45816; C07222; 2-(2-((3-(1H-Benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetate (1S-cis)-; BRD-K09549677-300-01-8; Acetic acid, methoxy-, 2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, (1S-cis)-; AC1Q4NDV; [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate; NCGC00161420-01; NCGC00161420-03; Lopac-M-5441; Mibefradil; (1S-cis)-2-(2-((3-(1H-Benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetate; NCGC00015683-01; 116644-53-2; 116666-63-8 (dihydrochloride); Mibefradil (INN); Lopac0_000748; LS-172325; NCGC00161420-04; Mibefradil [INN:BAN]; (1s,2s)-2-[2-[[3-(2-benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate; D08217    

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CAS NumberCAS 116644-53-2
PubChem Compound IDCID 60663.    
PubChem Substance IDSID 9431.    
SuperDrug ATC IDC08CX01;    
SuperDrug CAS ID116644532;    
TargetVoltage-dependent T-type calcium channelBlocker[1][2][3][4]
Ref 1T-type calcium channel blockade in the management of chronic ischemic heart disease. Cardiovasc Drugs Ther. 2000 Oct;14(5):459-61. To Reference
Ref 2Comparison of the efficacy and safety of losartan (50-100 mg) with the T-type calcium channel blocker mibefradil (50-100 mg) in mild to moderate hypertension. Fundam Clin Pharmacol. 2000 Jan-Feb;14(1):31-41. To Reference
Ref 3Determinants of voltage-dependent inactivation affect Mibefradil block of calcium channels. Neuropharmacology. 2000;39(1):1-10. To Reference
Ref 4Voltage-gated T-type Ca2+ channels and heart failure. Proc Assoc Am Physicians. 1999 Sep-Oct;111(5):429-37. To Reference


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