Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DCL000344

Drug Information
NameTykerb    
SynonymsCID11557040; CHEMBL1201179; Lapatinib ditosylate (USAN); GW-572016F; GW-572016; Lapatinib tosilate hydrate (JAN); Lapatinib tosilate hydrate; Lapatinib Ditosylate; LAPATINIB DITOSYLATE MONOHYDRATE; Tykerb (TN); Tykerb; Tyverb; D04024; GW-2016; 388082-78-8    
CompanyGSK    
IndicationBladder, head & neck, NSCLC, brain cancerPhase II completed    
Refractory metastatic breast cancer, RCCPhase III    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 388082-78-8
Formular C29H26ClFN4O4S    
PubChem Compound IDCID 11557040.    
PubChem Substance IDSID 12015501.    
ChEBI49603;    
ClinicalTrials.govNCT00073008;    
NCT00558103;    
TargetEpidermal growth factor receptorInhibitor[1]
Epidermal growth factor receptorMultitarget[1]
Erbb2Inhibitor[1]
Erbb2Multitarget[1]
Ref 1A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

 
   
           
 
Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543