TTD Drug ID: DCL000366

Drug Information
Name	Ro 31-7453
Synonyms	AC1NS2UU; CID5327686; Bisindolylmaleimide deriv. 44; Ro-31-7453; 3-(1-methylindol-3-yl)-4-(1-methyl-6-nitroindol-3-yl)pyrrole-2,5-dione; MKC-1; CHEMBL52885
Company	Hoffmann La Roche
Indication	Ovarian Cancer; Endometrial Cancer			Phase II
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Therapeutic Class	Antineoplastic Agents
CAS Number	CAS 443912-18-3
PubChem Compound ID	CID 5327686.
PubChem Substance ID	SID 8032392.
ClinicalTrials.gov	NCT00607607;
Target	Cell division protein kinase 1			Inhibitor	[1]
	Cell division protein kinase 1			Multitarget	[1]
	Cell division protein kinase 2			Inhibitor	[1]
	Cell division protein kinase 2			Multitarget	[1]
	Cell division protein kinase 4			Inhibitor	[1]
	Cell division protein kinase 4			Multitarget	[1]
Ref 1	A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Curr Top Med Chem. 2007;7(14):1408-22. To Reference

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.