Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL000680

Drug Information
SynonymsWY 50324; N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]adamantane-1-carboxamide; Adatanserin [INN]; Tricyclo(,7))decane-1-carboxamide, N-(2-(4-(2-pyrimidinyl)-1-piperazinyl)ethyl)-; CID130918; UNII-W5U6WQM26H; L001372; AC1L2Y9D; Adatanserin; 144966-96-1 (Monohydrochloride); 127266-56-2    
IndicationSevere Mood DisordersDiscontinued in Phase II    [1]

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
CAS NumberCAS 127266-56-2
PubChem Compound IDCID 130918.    
PubChem Substance IDSID 707386.    
Target5-hydroxytryptamine receptor 1A Multitarget[1][2]
5-hydroxytryptamine receptor 1A Agonist[1][2]
5-hydroxytryptamine receptor 2A Antagonist[1][2]
5-hydroxytryptamine receptor 2A Multitarget[1][2]
Ref 1Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2. To Reference
Ref 2J Med Chem. 1999 Dec 16;42(25):5077-94.Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543