Therapeutic Targets Database
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TTD Drug ID: DCL000703

Drug Information
NameAsenapine    
SynonymsEINECS 265-829-4; 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-met; trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole; PDSP2_001584; hyl-, trans-; Org-5222; 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bR)-rel-; Org 5222; Asenapi; 65576-45-6; Asenapine; UNII-JKZ19V908O; AC1L4SHR; 1H-Dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bR)-rel-; PDSP1_001600; 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3-6,7)oxepino(4,5-c)pyrrole; 1H-Dibenz(2,3:6,7)oxepino(4,5-c)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-; CHEMBL504548; [13C,2H3]-Asenipine; Asenapine [INN:BAN]; CID163091; I14-8821; 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, trans-; 135882-95-0    
Trade NameSaphris    
CompanyOrganon BioSciences (now a subsidiary of Merck)    
IndicationSchizophrenia and bipolar disorderApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
CAS NumberCAS 65576-45-6
FormularC17H16ClNO    
PubChem Compound IDCID 163091.    
PubChem Substance IDSID 740601.    
SuperDrug ATC IDJ04AD02;    
SuperDrug CAS ID000910861;    
Target5-hydroxytryptamine receptor 2A Multitarget[1][2]
D(2) dopamine receptor Antagonist[1][2]
5-hydroxytryptamine receptor 2A Antagonist[1][2]
D(2) dopamine receptor Multitarget[1][2]
Ref 1Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92. To Reference
Ref 2Emerging drugs for bipolar disorder. Expert Opin Emerg Drugs. 2006 Nov;11(4):621-34. To Reference



 

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