Therapeutic Targets Database
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TTD Drug ID: DCL000881

Drug Information
NameMethylnaltrexone    
SynonymsNaltrexone MB; methyl-naltrexone hydrobromide; C21H26NO4; CID5361918; 83387-25-1; MRZ 2663BR; LS-177749; Quaternary ammonium naltrexone; UNII-0RK7M7IABE; naltrexonium methiodide; N-Methylnaltrexone; 17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium; Mrz-2663; Methylnaltrexone; CID11639740; CID11992464; NALTREXONE METHYLBROMIDE; Methylnaltrexonium; 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one; Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, (5alpha)-    
CompanyWyeth and Progenics    
IndicationConstipation, Postoperative ileusPhase IV completed    [1]
Structure

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CAS NumberCAS 83387-25-1
FormularC21H26NO4+    
PubChem Compound IDCID 11992464.    
PubChem Substance IDSID 37440843.    
ClinicalTrials.govNCT00949377;    
TargetMu-type opioid receptor Antagonist[1]
Ref 1Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26. To Reference



 

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