Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DCL001078

Drug Information
Synonyms5-Amido-pyrrolopyrazole 9d; CID11442891; UNII-M3X659D0FY; S1107_Selleck; Danusertib, PHA-739358; CID 11994441; CHEMBL402548; PHA-739358; I06-2258; PHA 739358; Danusertib; (R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide; Benzamide, 4-(4-methyl-1-piperazinyl)-N-(1,4,5,6-tetrahydro-5-((2R)- methoxyphenylacetyl)pyrrolo(3,4-c)pyrazol-3-yl)-; 2j50; EC-000.2352; EN003071; 827318-97-8    
IndicationCML that relapsed after imatinib or BCR¨CABL-targeted therapy; Metastatic Hormone Refractory Prostate Cancer (MHRPC)Phase II    

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PubChem Compound IDCID 11442891.    
PubChem Substance IDSID 16541138.    
TargetAurora AInhibitor[1]
Aurora AMultitarget[1]
Aurora BInhibitor[1]
Aurora BMultitarget[1]
Ref 1Nat Rev Drug Discov. 2009 Jul;8(7):547-66.Cell cycle kinases as therapeutic targets for cancer. To Reference


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