Therapeutic Targets Database
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TTD Drug ID: DCL001085

Drug Information
NameBEZ235    
SynonymsBEZ235; NVP-BEZ235, BEZ235; CID11977753; EC-000.2325; BEZ-235; 2-(4-(2,3-dihydro-3-methyl-2-oxo-8-(quinolin-3-yl)imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile; Kinome_2911; ZINC24760115; S14-0511; CID 11977753; NVP-BEZ-235; S1009_Selleck; nchembio.117-comp24; ST51056474; MolPort-005-737-784    
CompanyNovartis    
IndicationAdvanced solid tumours; Advanced breast cancerPhase I/II    
Structure

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Click to save drug structure in 2D MOL format
   
PubChem Compound IDCID 11977753.    
PubChem Substance IDSID 17429886.    
ClinicalTrials.govNCT01195376;    
TargetPI3KInhibitor[1]
PI3KMultitarget[1]
Serine/threonine-protein kinase mTORInhibitor[1]
Serine/threonine-protein kinase mTORMultitarget[1]
Ref 1Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov. 2009 Aug;8(8):627-44. To Reference



 

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