Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC000017

Drug Information
Name(S)-Rolipram    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
CAS NumberCAS 216974-75-3
PubChem Compound IDCID 158758.    
PubChem Substance IDSID 736201.    
TargetCAMP-specific 3',5'-cyclic phosphodiesterase 4AInhibitor[1]
CAMP-specific 3',5'-cyclic phosphodiesterase 4BInhibitor[1]
Phosphodiesterase isozyme 4Inhibitor[1][2]
Ref 1PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L959-69. Epub 2009 Mar 20. To Reference
Ref 2Phosphodiesterase 4 in osteoblastic osteosarcoma cells as a potential target for growth inhibition. Anticancer Drugs. 2003 Jun;14(5):377-81. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

 
   
           
 
Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543