Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC000933

Drug Information
NameMethotrexate    
Structure

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CAS NumberCAS 142155-43-9
PubChem Compound IDCID 126941.    
PubChem Substance IDSID 5042.    
ChEBI44185;    
SuperDrug ATC IDL01BA01;    
SuperDrug CAS ID000059052;    
TargetDihydrofolate reductaseInhibitor[1][2][3]
Ref 1Anticancer antifolates: current status and future directions. Curr Pharm Des. 2003;9(31):2593-613. To Reference
Ref 2Deaza analogs of folic acid as antitumor agents. Curr Pharm Des. 2003;9(31):2615-25. To Reference
Ref 3Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines. Int J Cancer. 2003 Feb 20;103(5):587-99. To Reference



 

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