Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC001217

Drug Information

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
CAS NumberCAS 87051-43-2
PubChem Compound IDCID 5074.    
PubChem Substance IDSID 193052.    
Target5-hydroxytryptamine 2 receptorAntagonist[1][2][3][4]
5-hydroxytryptamine 2A receptorAntagonist[1][5][6]
5-hydroxytryptamine 2B receptorAntagonist[6]
5-hydroxytryptamine 2C receptorAntagonist[1][2][3][4]
5-hydroxytryptamine receptorAntagonist[4]
Ref 1Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat. Eur J Pharmacol. 2008 Sep 11;592(1-3):133-7. Epub 2008 Jul 4. To Reference
Ref 2Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo. J Psychiatr Res. 2008 Sep;42(11):894-901. Epub 2008 Jun 3. To Reference
Ref 3Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice. Behav Pharmacol. 2008 Mar;19(2):145-52. To Reference
Ref 4Combined treatment of portal hypertension with ritanserin and propranolol in conscious and unrestrained cirrhotic rats. Hepatology. 1992 May;15(5):878-82. To Reference
Ref 5Human embryonic stem cell-derived oligodendrocyte progenitor cells express the serotonin receptor and are susceptible to JC virus infection. J Virol. 2008 Sep;82(17):8896-9. Epub 2008 Jun 25. To Reference
Ref 6p-Chloroamphetamine, a serotonin-releasing drug, elicited in rats a hyperglycemia mediated by the 5-HT1A and 5-HT2B/2C receptors. Eur J Pharmacol. 1998 Oct 23;359(2-3):185-90. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543