Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC001276

Drug Information
NameSB 202190    
IndicationPainExperimental    
Structure

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Therapeutic ClassAnalgesics    
CAS NumberCAS 152121-30-7
PubChem Compound IDCID 5353940.    
PubChem Substance IDSID 647319.    
TargetMitogen-activated protein kinase 14Inhibitor[1]
Prostaglandin G/H synthase 2Inhibitor[2]
Ref 1Inhibition of p38 MAPK decreases myocardial TNF-alpha expression and improves myocardial function and survival in endotoxemia. Cardiovasc Res. 2003 Oct 1;59(4):893-900. To Reference
Ref 2A selective inhibitor of p38 MAP kinase, SB202190, induced apoptotic cell death of a lipopolysaccharide-treated macrophage-like cell line, J774.1. Biochim Biophys Acta. 2000 Oct 18;1502(2):207-23. To Reference



 

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