Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC001280

Drug Information
NameSB 203580    

Click to save drug structure in 3D MOL format

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CAS NumberCAS 152121-47-6
PubChem Compound IDCID 176155.    
PubChem Substance IDSID 753357.    
TargetInterleukin 1 receptorAntagonist[1]
Mitogen-activated protein kinase 14Inhibitor[2][3]
Prostaglandin G/H synthase 2Inhibitor[4]
Ref 1IL-1- and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase. J Cell Physiol. 2001 Jun;187(3):294-303. To Reference
Ref 2The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment. Blood. 2001 Aug 1;98(3):667-73. To Reference
Ref 3Mini Rev Med Chem. 2007 Nov;7(11):1108-19.Privileged structures: a useful concept for the rational design of new lead drug candidates. To Reference
Ref 4Inhibition of p38 MAP kinase as a therapeutic strategy. Immunopharmacology. 2000 May;47(2-3):185-201. To Reference


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