Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003799

Drug Information

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TargetDopamine D1 receptorInhibitor[1]
Dopamine D2 receptorInhibitor[2]
Dopamine D3 receptorInhibitor[3]
Dopamine D4 receptorInhibitor[2]
Serotonin 1a (5-HT1a) receptorInhibitor[4]
Serotonin 2a (5-HT2a) receptorInhibitor[4]
Serotonin 6 (5-HT6) receptorInhibitor[4]
Serotonin 7 (5-HT7) receptorInhibitor[4]
Ref 1Bioorg Med Chem. 2009 Jul 1;17(13):4448-58. Epub 2009 May 12.Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases. To Reference
Ref 2Bioorg Med Chem. 2009 Feb 15;17(4):1716-23. Epub 2008 Dec 31.Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups. To Reference
Ref 3Bioorg Med Chem Lett. 1999 Feb 22;9(4):585-8.Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. To Reference
Ref 4Bioorg Med Chem Lett. 2001 Jun 4;11(11):1375-7.Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. To Reference


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