Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003939

Drug Information

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TargetAlpha-1a adrenergic receptorInhibitor[1]
Alpha-1b adrenergic receptorInhibitor[1]
Alpha-1d adrenergic receptorInhibitor[1]
Alpha-2a adrenergic receptorInhibitor[2]
Alpha-2b adrenergic receptorInhibitor[2]
Alpha-2c adrenergic receptorInhibitor[2]
Voltage-gated L-type calcium channel alpha-1C subunitInhibitor[2]
Voltage-gated L-type calcium channel alpha-1D subunitInhibitor[3]
Ref 1J Med Chem. 1995 Sep 15;38(19):3681-716.Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications. To Reference
Ref 2Bioorg Med Chem Lett. 1999 Oct 4;9(19):2843-8.Design and synthesis of novel dihydropyridine alpha-1a antagonists. To Reference
Ref 3J Med Chem. 1995 May 12;38(10):1579-81.Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine. To Reference


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