Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC003974

Drug Information
NameDITOLYLGUANIDINE    
SynonymsDITOLYLGUANIDINE    
Structure

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TargetGlutamate (NMDA) receptor subunit zeta 1Inhibitor[1]
Glutamate [NMDA] receptor subunit epsilon 1Inhibitor[1]
Glutamate [NMDA] receptor subunit epsilon 2Inhibitor[1]
Sigma opioid receptorInhibitor[2]
Ref 1J Med Chem. 1998 Aug 13;41(17):3298-302.Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents. To Reference
Ref 2J Med Chem. 1994 Jun 10;37(12):1737-9.Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells. To Reference



 

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