Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC004129

Drug Information
Name(+)-NIGULDIPINE    
Synonyms(+)-NIGULDIPINE    
Structure

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TargetAdenosine A3 receptorInhibitor[1]
Alpha-1a adrenergic receptorInhibitor[2]
Voltage-gated L-type calcium channel alpha-1C subunitInhibitor[3]
Voltage-gated L-type calcium channel alpha-1D subunitInhibitor[3]
Ref 1J Med Chem. 1999 Aug 12;42(16):3055-65.Chiral resolution and stereospecificity of 6-phenyl-4-phenylethynyl- 1,4-dihydropyridines as selective A(3) adenosine receptor antagonists. To Reference
Ref 2Bioorg Med Chem Lett. 2005 Feb 1;15(3):657-64.Pharmacophore identification of alpha(1A)-adrenoceptor antagonists. To Reference
Ref 3J Med Chem. 1995 May 12;38(10):1579-81.Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine. To Reference



 

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