Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC004182

Drug Information
NameL-741742    
Structure

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TargetDopamine D3 receptorInhibitor[1]
Dopamine D4 receptorInhibitor[1]
Sodium channel protein type I alpha subunitInhibitor[2]
Sodium channel protein type III alpha subunitInhibitor[2]
Ref 1J Med Chem. 1996 May 10;39(10):1943-5.5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors. To Reference
Ref 2J Med Chem. 1999 Jul 15;42(14):2706-15.1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: a selective high-affinity antagonist for the human dopamine D(4) receptor with excellent selectivity over ion channels. To Reference



 

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