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|Target||Macrophage colony stimulating factor receptor ||Inhibitor|||
|Tyrosine-protein kinase receptor FLT3||Inhibitor|||
|Ref 1||J Med Chem. 2002 Aug 15;45(17):3772-93.Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase family. To Reference|
|Ref 2||Blood. 2009 Oct 1;114(14):2984-92. Epub 2009 Aug 4.AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). To Reference|
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Deputy Director of Center
for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
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