Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC004233

Drug Information
NameMLN-518    
Structure

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TargetMacrophage colony stimulating factor receptor Inhibitor[1]
Tyrosine-protein kinase receptor FLT3Inhibitor[2]
Ref 1J Med Chem. 2002 Aug 15;45(17):3772-93.Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase family. To Reference
Ref 2Blood. 2009 Oct 1;114(14):2984-92. Epub 2009 Aug 4.AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). To Reference



 

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