TTD Drug ID: DNC004908

Drug Information
Name	1-(2-Methoxy-phenyl)-piperazine
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Target	Alpha-1a adrenergic receptor			Inhibitor	[1]
	Alpha-1a adrenergic receptor			Inhibitor	[1]
	Serotonin 1a (5-HT1a) receptor			Inhibitor	[1]
	Serotonin 1d (5-HT1d) receptor			Inhibitor	[2]
	Serotonin 2a (5-HT2a) receptor			Inhibitor	[3]
	Serotonin 6 (5-HT6) receptor			Inhibitor	[4]
Ref 1	J Med Chem. 1991 Jun;34(6):1850-4.Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. To Reference
Ref 2	J Med Chem. 1989 May;32(5):1052-6.Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. To Reference
Ref 3	J Med Chem. 1986 May;29(5):630-4.Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents. To Reference
Ref 4	Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands. To Reference

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