Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC004908

Drug Information

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TargetAlpha-1a adrenergic receptorInhibitor[1]
Alpha-1a adrenergic receptorInhibitor[1]
Serotonin 1a (5-HT1a) receptorInhibitor[1]
Serotonin 1d (5-HT1d) receptorInhibitor[2]
Serotonin 2a (5-HT2a) receptorInhibitor[3]
Serotonin 6 (5-HT6) receptorInhibitor[4]
Ref 1J Med Chem. 1991 Jun;34(6):1850-4.Pyrimido[5,4-b]indole derivatives. 1. A new class of potent and selective alpha 1 adrenoceptor ligands. To Reference
Ref 2J Med Chem. 1989 May;32(5):1052-6.Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. To Reference
Ref 3J Med Chem. 1986 May;29(5):630-4.Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents. To Reference
Ref 4Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands. To Reference


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