Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC006944

Drug Information
NameAZD-1152-HQPA;Barasertib    
Structure

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TargetSerine/threonine-protein kinase Aurora-AInhibitor[1]
Serine/threonine-protein kinase Aurora-BInhibitor[2]
Serine/threonine-protein kinase Aurora-CInhibitor[1]
Tyrosine-protein kinase LCKInhibitor[1]
Vascular endothelial growth factor receptor 2Inhibitor[1]
Ref 1J Med Chem. 2007 May 3;50(9):2213-24. Epub 2007 Mar 21.Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase. To Reference
Ref 2J Med Chem. 2009 May 14;52(9):2629-51.Discovery and development of aurora kinase inhibitors as anticancer agents. To Reference



 

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