Therapeutic Targets Database
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TTD Drug ID: DNC008664

Drug Information
NameBMS-694153    
Structure

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TargetCalcitonin gene-related peptide type 1 receptorInhibitor[1]
Cytochrome P450 2D6Inhibitor[1]
Ref 1J Med Chem. 2008 Aug 28;51(16):4858-61. Epub 2008 Jul 30.Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure. To Reference



 

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