TTD Drug ID: DNC009423

Drug Information
Name	SIPATRIGINE
Synonyms	SIPATRIGINE
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Target	Sodium channel protein type I alpha subunit			Inhibitor	[1]
	Sodium channel protein type III alpha subunit			Inhibitor	[1]
	Sodium channel protein type IV alpha subunit			Inhibitor	[2]
	Sodium channel protein type IX alpha subunit			Inhibitor	[2]
	Sodium channel protein type V alpha subunit			Inhibitor	[3]
	Sodium channel protein type VI alpha subunit			Inhibitor	[3]
	Sodium channel protein type X alpha subunit			Inhibitor	[2]
	Voltage-gated L-type calcium channel alpha-1D subunit			Inhibitor	[4]
Ref 1	J Med Chem. 2002 Aug 15;45(17):3755-64.Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke. To Reference
Ref 2	J Med Chem. 2009 May 14;52(9):2694-707.Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. To Reference
Ref 3	J Med Chem. 2001 Jan 18;44(2):115-37.Medicinal chemistry of neuronal voltage-gated sodium channel blockers. To Reference
Ref 4	Bioorg. Med. Chem. Lett. 5(19):2259-2262 (1995) To Reference

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