Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC009423

Drug Information
NameSIPATRIGINE    
SynonymsSIPATRIGINE    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
TargetSodium channel protein type I alpha subunitInhibitor[1]
Sodium channel protein type III alpha subunitInhibitor[1]
Sodium channel protein type IV alpha subunitInhibitor[2]
Sodium channel protein type IX alpha subunitInhibitor[2]
Sodium channel protein type V alpha subunitInhibitor[3]
Sodium channel protein type VI alpha subunit Inhibitor[3]
Sodium channel protein type X alpha subunitInhibitor[2]
Voltage-gated L-type calcium channel alpha-1D subunitInhibitor[4]
Ref 1J Med Chem. 2002 Aug 15;45(17):3755-64.Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke. To Reference
Ref 2J Med Chem. 2009 May 14;52(9):2694-707.Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. To Reference
Ref 3J Med Chem. 2001 Jan 18;44(2):115-37.Medicinal chemistry of neuronal voltage-gated sodium channel blockers. To Reference
Ref 4Bioorg. Med. Chem. Lett. 5(19):2259-2262 (1995) To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

 
   
           
 
Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543