Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DNC009882

Drug Information
NameTiotropium Bromide    
TargetMuscarinic acetylcholine receptor M1Inhibitor[1]
Muscarinic acetylcholine receptor M2Inhibitor[1]
Muscarinic acetylcholine receptor M3Inhibitor[1]
Ref 1J Med Chem. 2009 Aug 27;52(16):5076-92.Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide). To Reference



 

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