TTD Drug ID: DNC010258

Drug Information
Name	(+/-)-nantenine
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Target	Serotonin 5a (5-HT5a) receptor			Inhibitor	[1]
	Serotonin 6 (5-HT6) receptor			Inhibitor	[1]
	Alpha-1b adrenergic receptor			Inhibitor	[1]
	Alpha-2a adrenergic receptor			Inhibitor	[1]
	Alpha-2c adrenergic receptor			Inhibitor	[1]
	Dopamine D1 receptor			Inhibitor	[1]
	Dopamine D3 receptor			Inhibitor	[1]
	Serotonin 2c (5-HT2c) receptor			Inhibitor	[1]
	Serotonin 2b (5-HT2b) receptor			Inhibitor	[1]
	Serotonin 2a (5-HT2a) receptor			Inhibitor	[1]
	Serotonin 1d (5-HT1d) receptor			Inhibitor	[1]
	Serotonin 1b (5-HT1b) receptor			Inhibitor	[1]
	Mu opioid receptor			Inhibitor	[1]
	Histamine H2 receptor			Inhibitor	[1]
	Dopamine D5 receptor			Inhibitor	[1]
	Dopamine D4 receptor			Inhibitor	[1]
	Dopamine D2 receptor			Inhibitor	[1]
	Beta-1 adrenergic receptor			Inhibitor	[1]
	Alpha-2b adrenergic receptor			Inhibitor	[1]
	Alpha-1d adrenergic receptor			Inhibitor	[1]
	Alpha-1a adrenergic receptor			Inhibitor	[1]
	Serotonin 7 (5-HT7) receptor			Inhibitor	[1]
	Serotonin transporter			Inhibitor	[1]
Ref 1	Bioorg Med Chem Lett. 2010 Jan 15;20(2):628-31. Epub 2009 Nov 20.Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine. To Reference

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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