Therapeutic Targets Database
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TTD Drug ID: DNC011171

Drug Information
Name4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one    
Structure

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TargetMuscarinic acetylcholine receptor M5Inhibitor[1]
Neurokinin 1 receptorInhibitor[1]
Neurokinin 2 receptorInhibitor[1]
Neuronal acetylcholine receptor protein alpha-4 subunitInhibitor[1]
Neuronal acetylcholine receptor protein beta-2 subunitInhibitor[1]
Neuropeptide Y receptor type 1Inhibitor[1]
Neurotensin receptor 1Inhibitor[1]
Norepinephrine transporterInhibitor[1]
Serotonin 1a (5-HT1a) receptorInhibitor[1]
Beta-1 adrenergic receptorInhibitor[1]
Alpha-2a adrenergic receptorInhibitor[1]
Alpha-1d adrenergic receptorInhibitor[1]
Alpha-1b adrenergic receptorInhibitor[1]
Alpha-1a adrenergic receptorInhibitor[1]
Adenosine A3 receptorInhibitor[1]
Adenosine A2a receptorInhibitor[1]
Adenosine A1 receptorInhibitor[1]
AcetylcholinesteraseInhibitor[1]
Muscarinic acetylcholine receptor M3Inhibitor[1]
Muscarinic acetylcholine receptor M2Inhibitor[1]
Muscarinic acetylcholine receptor M1Inhibitor[1]
Mu opioid receptorInhibitor[1]
Melatonin receptor 1AInhibitor[1]
Melanocortin receptor 4Inhibitor[1]
Histamine H3 receptorInhibitor[1]
Histamine H2 receptorInhibitor[1]
Histamine H1 receptorInhibitor[1]
Muscarinic acetylcholine receptor M4Inhibitor[1]
Glucocorticoid receptorInhibitor[1]
Endothelin receptor ET-AInhibitor[1]
Dopamine transporterInhibitor[1]
Dopamine D3 receptorInhibitor[1]
Dopamine D2 receptorInhibitor[1]
Dopamine D1 receptorInhibitor[1]
Cholecystokinin B receptorInhibitor[1]
Cannabinoid CB1 receptorInhibitor[1]
Serotonin 2a (5-HT2a) receptorInhibitor[1]
Serotonin 2b (5-HT2b) receptorInhibitor[1]
Serotonin 2c (5-HT2c) receptorInhibitor[1]
Serotonin 3a (5-HT3a) receptorInhibitor[1]
Serotonin 4 (5-HT4) receptorInhibitor[1]
Serotonin 7 (5-HT7) receptorInhibitor[1]
Serotonin transporterInhibitor[1]
Ref 1J Med Chem. 2010 Sep 9;53(17):6386-97.Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential. To Reference



 

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Professor in Department of Pharmacy
National University of Singapore, Singapore


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