TTD Drug ID: DNC011857

Drug Information
Name	FLUMEZAPINE
Synonyms	FLUMEZAPINE
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Target	Dopamine D1 receptor			Inhibitor	[1]
	Dopamine D2 receptor			Inhibitor	[2]
	Dopamine D3 receptor			Inhibitor	[1]
	Dopamine D4 receptor			Inhibitor	[1]
	Dopamine D5 receptor			Inhibitor	[1]
	Muscarinic acetylcholine receptor M1			Inhibitor	[2]
	Muscarinic acetylcholine receptor M2			Inhibitor	[2]
	Muscarinic acetylcholine receptor M3			Inhibitor	[2]
	Muscarinic acetylcholine receptor M4			Inhibitor	[2]
	Muscarinic acetylcholine receptor M5			Inhibitor	[2]
Ref 1	J Med Chem. 1982 Oct;25(10):1133-40.Effects of conformationally restricted 4-piperazinyl-10H-thienobenzodiazepine neuroleptics on central dopaminergic and cholinergic systems. To Reference
Ref 2	J Med Chem. 1989 Dec;32(12):2573-82.Synthesis and pharmacological evaluation of a series of 4-piperazinylpyrazolo[3,4-b]- and -[4,3-b][1,5]benzodiazepines as potential anxiolytics. To Reference

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.