Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Target ID: TTDS00225

Target Information
NameDNA-dependent RNA polymerase    
Type of targetSuccessful target    
DiseaseTuberculosis    [1]
Drug(s)RifapentineApprovedTuberculosis[2]
BinderCBR-2092[3]
Rifapentine[2]
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1First insight into genetic diversity of the Mycobacterium tuberculosis complex in Albania obtained by multilocus variable-number tandem-repeat analysis and spoligotyping reveals the presence of beijing multidrug-resistant isolates. J Clin Microbiol. 2009 May;47(5):1581-4. Epub 2009 Mar 11. To Reference
Ref 2Contribution of rpoB mutations to development of rifamycin cross-resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1998 Jul;42(7):1853-7. To Reference
Ref 3How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference



 

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