Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Target ID: TTDS00461

Target Information
Name26S proteasome    
Type of targetSuccessful target    
DiseaseMultiple myeloma    [1]
Drug(s)BortezomibApprovedMultiple myeloma[1]
BortezomibPhase IIIFollicular NHL and MCL[1][2][3]
BioChemical ClassProtease    
Target ValidationClick to Find Target Validation Information.    
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Bortezomib: a novel chemotherapeutic agent for hematologic malignancies. Am J Health Syst Pharm. 2008 Jul 1;65(13):1221-31. To Reference
Ref 2Takeda. Product Development Pipeline. July 31 2009. To Reference
Ref 3Phase II study of the proteasome inhibitor bortezomib (PS-341, Velcade((R))) in chemotherapy-na?¡¥ve patients with advanced stage non-small cell lung cancer (NSCLC). Lung Cancer. 2009 Jun 11. [Epub ahead of print] To Reference


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